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HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53‐dependent mitochondrial apoptosis
Apoptotic signalling by p53 occurs at both transcriptional and non‐transcriptional levels, as p53 may act as a direct apoptogenic stimulus via activation of the intrinsic mitochondrial pathway. HOPS is a highly conserved, ubiquitously expressed shuttling protein with an ubiquitin‐like domain. We gen...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7001502/ https://ncbi.nlm.nih.gov/pubmed/31867855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948073 |
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