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DDB2 association with PCNA is required for its degradation after UV-induced DNA damage

DDB2 is a protein playing an essential role in the lesion recognition step of the global genome sub-pathway of nucleotide excision repair (GG-NER) process. Among the proteins involved in the DNA damage response, p21(CDKN1A) (p21) has been reported to participate in NER, but also to be removed by pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cazzalini, Ornella, Perucca, Paola, Mocchi, Roberto, Sommatis, Sabrina, Prosperi, Ennio, Stivala, Lucia Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906241/
https://ncbi.nlm.nih.gov/pubmed/24200966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26987
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