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High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules.

Proteins that have been modified by long-term exposure to glucose accumulate advanced glycosylation end products (AGE) as a function of protein age. In these studies, we have characterized the interaction of AGE-protein with mouse peritoneal macrophages, using AGE-modified bovine serum albumin (AGE-...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Vlassara, H, Brownlee, M, Cerami, A
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390596/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994035/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.17.5588
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