High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules.

Proteins that have been modified by long-term exposure to glucose accumulate advanced glycosylation end products (AGE) as a function of protein age. In these studies, we have characterized the interaction of AGE-protein with mouse peritoneal macrophages, using AGE-modified bovine serum albumin (AGE-...

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Main Authors: Vlassara, H, Brownlee, M, Cerami, A
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC390596/
https://ncbi.nlm.nih.gov/pubmed/2994035
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