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N-myc can cooperate with ras to transform normal cells in culture.

N-myc, a cellular gene bearing homology to the c-myc protooncogene, is frequently amplified and overexpressed in a highly restricted set of related tumors, most notably neuroblastomas and retinoblastomas. We have examined the possibility that N-myc may play a causal role in the genesis of these tumo...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Yancopoulos, G D, Nisen, P D, Tesfaye, A, Kohl, N E, Goldfarb, M P, Alt, F W
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1985
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390588/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3860871/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.16.5455
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