N-myc can cooperate with ras to transform normal cells in culture.
N-myc, a cellular gene bearing homology to the c-myc protooncogene, is frequently amplified and overexpressed in a highly restricted set of related tumors, most notably neuroblastomas and retinoblastomas. We have examined the possibility that N-myc may play a causal role in the genesis of these tumo...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3860871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.16.5455 |
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