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Pegylation of HDL Decreases Plasma Clearance and Enhances Anti-Atherogenic Activity

RATIONALE: Infusions of apoA-I, mimetic peptides or HDL remain a promising approach to treatment of atherosclerotic coronary disease. However, rapid clearance leads to a requirement for repeated administration of large amounts of material and limits effective plasma concentrations. OBJECTIVE: Since...

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Autori principali: Murphy, Andrew J., Funt, Samuel, Gorman, Darren, Tall, Alan R., Wang, Nan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905798/
https://ncbi.nlm.nih.gov/pubmed/23613182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301112
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