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Computing the relative stabilities, and the per-residue components, in protein conformational changes

Protein molecules often undergo conformational changes. In order to get insights about the forces that drive such changes, it would be useful to have a method that computes the per-residue contributions to the conversion free energy. Here, we describe the “Confine-Convert-Release” (CCR) method, whic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Roy, Arijit, Perez, Alberto, Dill, Ken A., MacCallum, Justin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905753/
https://ncbi.nlm.nih.gov/pubmed/24316402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.10.015
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