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Radiation inactivation of ricin occurs with transfer of destructive energy across a disulfide bridge.

The ionizing radiation sensitivity of ricin, a disulfide-linked heterodimeric protein, was studied as a model to determine the ability of disulfide bonds to transmit destructive energy. The radiation-dependent loss of A chain enzymatic activity after irradiation of either intact ricin or ricin in wh...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Haigler, H T, Woodbury, D J, Kempner, E S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390567/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3860867/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.16.5357
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