Hemin inhibits internalization of transferrin by reticulocytes and promotes phosphorylation of the membrane transferrin receptor.

Addition of hemin to reticulocytes inhibits incorporation of iron from transferrin [Ponka, P. & Neuwirt, J. (1969) Blood 33, 609-707]. Heme also regulates protein synthesis in immature erythroid cells through its effects on phosphorylation of the initiation factor eIF-2. We have therefore examin...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Cox, T M, O'Donnell, M W, Aisen, P, London, I M
Formato: Artigo
Idioma:Inglês
Publicado: 1985
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC390521/
https://ncbi.nlm.nih.gov/pubmed/2991909
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares