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Coordinated regulation of p31(Comet) and Mad2 expression is required for cellular proliferation

p31(Comet) is a well-known interacting partner of the spindle assembly checkpoint (SAC) effector molecule Mad2. At the molecular level it is well established that p31(Comet) promotes efficient mitotic exit, specifically the metaphase–anaphase transition, by antagonizing Mad2 function. However, there...

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Detalhes bibliográficos
Main Authors: Date, Dipali A, Burrows, Amy C, Venere, Monica, Jackson, Mark W, Summers, Matthew K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905074/
https://ncbi.nlm.nih.gov/pubmed/24131926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26811
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