Interferon-γ Induces Expression of MHC Class II on Intestinal Epithelial Cells and Protects Mice from Colitis

Immune responses against intestinal microbiota contribute to the pathogenesis of inflammatory bowel diseases (IBD) and involve CD4(+) T cells, which are activated by major histocompatibility complex class II (MHCII) molecules on antigen-presenting cells (APCs). However, it is largely unexplored how...

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Detalhes bibliográficos
Main Authors: Thelemann, Christoph, Eren, Remzi Onur, Coutaz, Manuel, Brasseit, Jennifer, Bouzourene, Hanifa, Rosa, Muriel, Duval, Anais, Lavanchy, Christine, Mack, Vanessa, Mueller, Christoph, Reith, Walter, Acha-Orbea, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904943/
https://ncbi.nlm.nih.gov/pubmed/24489792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086844
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