Nitrosonifedipine Ameliorates the Progression of Type 2 Diabetic Nephropathy by Exerting Antioxidative Effects

Diabetic nephropathy (DN) is the major cause of end-stage renal failure. Oxidative stress is implicated in the pathogenesis of DN. Nitrosonifedipine (NO-NIF) is a weak calcium channel blocker that is converted from nifedipine under light exposure. Recently, we reported that NO-NIF has potential as a...

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Autors principals: Ishizawa, Keisuke, Izawa-Ishizawa, Yuki, Yamano, Noriko, Urushihara, Maki, Sakurada, Takumi, Imanishi, Masaki, Fujii, Shoko, Nuno, Asami, Miyamoto, Licht, Kihira, Yoshitaka, Ikeda, Yasumasa, Kagami, Shoji, Kobori, Hiroyuki, Tsuchiya, Koichiro, Tamaki, Toshiaki
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904885/
https://ncbi.nlm.nih.gov/pubmed/24489716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086335
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