TFPI1 Mediates Resistance to Doxorubicin in Breast Cancer Cells by Inducing a Hypoxic-Like Response

Thrombin and hypoxia are important players in breast cancer progression. Breast cancers often develop drug resistance, but mechanisms linking thrombin and hypoxia to drug resistance remain unresolved. Our studies using Doxorubicin (DOX) resistant MCF7 breast cancer cells reveals a mechanism linking...

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Detalhes bibliográficos
Main Authors: Davies, Gerald F., Berg, Arnie, Postnikoff, Spike D. L., Wilson, Heather L., Arnason, Terra G., Kusalik, Anthony, Harkness, Troy A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904823/
https://ncbi.nlm.nih.gov/pubmed/24489651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084611
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