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The SNF1 Kinase Ubiquitin-associated Domain Restrains Its Activation, Activity, and the Yeast Life Span

The enzyme family of heterotrimeric AMP-dependent protein kinases is activated upon low energy states, conferring a switch toward energy-conserving metabolic pathways through immediate kinase actions on enzyme targets and delayed alterations in gene expression through its nuclear relocalization. Thi...

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Pubblicato in:J Biol Chem
Autori principali: Jiao, Rubin, Postnikoff, Spike, Harkness, Troy A., Arnason, Terra G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505455/
https://ncbi.nlm.nih.gov/pubmed/25869125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647032
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