A Prospective, Multicenter, Phase I Matched-Comparison Group Trial of Safety, Pharmacokinetics, and Preliminary Efficacy of Riluzole in Patients with Traumatic Spinal Cord Injury

A prospective, multicenter phase I trial was undertaken by the North American Clinical Trials Network (NACTN) to investigate the pharmacokinetics and safety of, as well as obtain pilot data on, the effects of riluzole on neurological outcome in acute spinal cord injury (SCI). Thirty-six patients, wi...

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Détails bibliographiques
Auteurs principaux: Grossman, Robert G., Fehlings, Michael G., Frankowski, Ralph F., Burau, Keith D., Chow, Diana S.L., Tator, Charles, Teng, Angela, Toups, Elizabeth G., Harrop, James S., Aarabi, Bizhan, Shaffrey, Christopher I., Johnson, Michele M., Harkema, Susan J., Boakye, Maxwell, Guest, James D., Wilson, Jefferson R.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2014
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904533/
https://ncbi.nlm.nih.gov/pubmed/23859435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2013.2969
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