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Delayed Post-Injury Administration of Riluzole Is Neuroprotective in a Preclinical Rodent Model of Cervical Spinal Cord Injury

Riluzole, a sodium/glutamate antagonist has shown promise as a neuroprotective agent. It is licensed for amyotrophic lateral sclerosis and is in clinical trial development for spinal cord injury (SCI). This study investigated the therapeutic time-window and pharmacokinetics of riluzole in a rodent m...

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Detalhes bibliográficos
Main Authors: Wu, Yongchao, Satkunendrarajah, Kajana, Teng, Yang, Chow, Diana S.-L., Buttigieg, Josef, Fehlings, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696918/
https://ncbi.nlm.nih.gov/pubmed/23517137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2012.2622
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