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HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors

Motivation: Identification of expression Quantitative Trait Loci (eQTL), the genetic loci that contribute to heritable variation in gene expression, can be obstructed by factors that produce variation in expression profiles if these factors are unmeasured or hidden from direct analysis. Methods: We...

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Detalhes bibliográficos
Main Authors: Gao, Chuan, Tignor, Nicole L., Salit, Jacqueline, Strulovici-Barel, Yael, Hackett, Neil R., Crystal, Ronald G., Mezey, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904522/
https://ncbi.nlm.nih.gov/pubmed/24307700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt690
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