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Glutathione S-transferase Copy Number Variation Alters Lung Gene Expression

BACKGROUND: The glutathione S-transferase (GST) enzymes catalyze the conjugation of xenobiotics to glutathione. Based on reports that inherited copy number variations (CNV) modulate some GST gene expression levels, and that the small airway epithelium (SAE) and alveolar macrophages (AM) are involved...

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Detalles Bibliográficos
Main Authors: Butler, Marcus W., Hackett, Neil R, Salit, Jacqueline, Strulovici-Barel, Yael, Omberg, Larsson, Mezey, Jason, Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399270/
https://ncbi.nlm.nih.gov/pubmed/21349909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00029210
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