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Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

p60src, the transforming protein kinase of Rous sarcoma virus, contains the 14-carbon saturated fatty acid, myristic acid, linked through an amide bond to the alpha-amino group of its NH2-terminal glycine residue. Myristic acid is known to be attached to four other eukaryotic proteins. In each case...

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Hlavní autoři: Kamps, M P, Buss, J E, Sefton, B M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1985
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC390438/
https://ncbi.nlm.nih.gov/pubmed/2991884
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