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Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.
p60src, the transforming protein kinase of Rous sarcoma virus, contains the 14-carbon saturated fatty acid, myristic acid, linked through an amide bond to the alpha-amino group of its NH2-terminal glycine residue. Myristic acid is known to be attached to four other eukaryotic proteins. In each case...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1985
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390438/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991884/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.14.4625 |
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