The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity.
We have constructed two point mutants of Rous sarcoma virus in which the amino-terminal glycine residue of the transforming protein, p60src, was changed to an alanine or a glutamic acid residue. Both mutant proteins failed to become myristylated and, more importantly, no longer transformed cells. Th...
Sábháilte in:
| Foilsithe in: | J Virol |
|---|---|
| Príomhchruthaitheoirí: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
American Society for Microbiology (ASM)
1986
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3009860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.58.2.468-474.1986 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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