Structural invariants of antigen binding: comparison of immunoglobulin VL-VH and VL-VL domain dimers.
Antigen-combining site arises by noncovalent association of the variable domain of the immunoglobulin heavy chain (VH) with that of the light chain (VL). To analyze the invariant features of the binding region (VL-VH domain interface), we compared the known immunoglobulin three-dimensional structure...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1985
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390431/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3927286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.14.4592 |
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