Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin.

A cell culture of Taxus chinensis was established to produce the diterpene 2alpha,5alpha,10beta,14beta-tetra-acetoxy4 ++ +(20),11-taxadiene (taxuyunnanine C) in 2.6% (dry weight) yield. The incorporation of [U-13C6]glucose, [1-13C]glucose, and [1,2-13C2]acetate into this diterpene was analyzed by NM...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Eisenreich, W, Menhard, B, Hylands, P J, Zenk, M H, Bacher, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6431
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