Farnesoid X Receptor Ligand Prevents Cisplatin-Induced Kidney Injury by Enhancing Small Heterodimer Partner

The farnesoid X receptor (FXR) is mainly expressed in liver, intestine and kidney. We investigated whether 6-ethyl chenodeoxycholic acid (6ECDCA), a semisynthetic derivative of chenodeoxycholic aicd (CDCA, an FXR ligand), protects against kidney injury and modulates small heterodimer partner (SHP) i...

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Bibliographic Details
Main Authors: Bae, Eun Hui, Choi, Hong Sang, Joo, Soo Yeon, Kim, In Jin, Kim, Chang Seong, Choi, Joon Seok, Ma, Seong Kwon, Lee, JongUn, Kim, Soo Wan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903546/
https://ncbi.nlm.nih.gov/pubmed/24475141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086553
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