Paricalcitol Attenuates 4-Hydroxy-2-Hexenal-Induced Inflammation and Epithelial-Mesenchymal Transition in Human Renal Proximal Tubular Epithelial Cells

4-Hydroxy-2-hexenal (HHE), the aldehyde product of lipid peroxidation, may be responsible for the pathogenesis of progressive renal disease. Recently, paricalcitol (19-nor-1,25-dihydroxyvitamin D2) was shown to be renoprotective through its anti-inflammatory and antifibrotic effects in various exper...

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Hoofdauteurs: Kim, Chang Seong, Joo, Soo Yeon, Lee, Ko Eun, Choi, Joon Seok, Bae, Eun Hui, Ma, Seong Kwon, Kim, Suhn Hee, Lee, JongUn, Kim, Soo Wan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656901/
https://ncbi.nlm.nih.gov/pubmed/23690997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063186
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