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siRNA relieves chronic neuropathic pain

Double stranded, short interfering RNAs (siRNA) of 21–22 nt length initiate a sequence-specific, post-trancriptional gene silencing in animals and plants known as RNA interference (RNAi). Here we show that RNAi can block a pathophysiological pain response and provide relief from neuropathic pain in...

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Detalhes bibliográficos
Main Authors: Dorn, Gabriele, Patel, Sadhana, Wotherspoon, Glen, Hemmings-Mieszczak, Maja, Barclay, Jane, Natt, Francois J. C., Martin, Pierre, Bevan, Stuart, Fox, Alyson, Ganju, Pam, Wishart, William, Hall, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC390346/
https://ncbi.nlm.nih.gov/pubmed/15026538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh044
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