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Chemical synthesis and translesion replication of a cis–syn cyclobutane thymine–uracil dimer

The cytosine base in DNA undergoes hydrolytic deamination at a considerable rate when UV radiation induces formation of a cyclobutane pyrimidine dimer (CPD) with an adjacent pyrimidine base. We have synthesized a phosphoramidite building block of a cis–syn cyclobutane thymine–uracil dimer (T[]U), wh...

詳細記述

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書誌詳細
主要な著者: Takasawa, Kohei, Masutani, Chikahide, Hanaoka, Fumio, Iwai, Shigenori
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC390339/
https://ncbi.nlm.nih.gov/pubmed/15020710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh342
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