Preexisting CD8(+) T-cell immunity to the H7N9 influenza A virus varies across ethnicities

The absence of preexisting neutralizing antibodies specific for the novel A (H7N9) influenza virus indicates a lack of prior human exposure. As influenza A virus–specific CD8(+) T lymphocytes (CTLs) can be broadly cross-reactive, we tested whether immunogenic peptides derived from H7N9 might be reco...

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Hauptverfasser: Quiñones-Parra, Sergio, Grant, Emma, Loh, Liyen, Nguyen, Thi H. O., Campbell, Kristy-Anne, Tong, Steven Y. C., Miller, Adrian, Doherty, Peter C., Vijaykrishna, Dhanasekaran, Rossjohn, Jamie, Gras, Stephanie, Kedzierska, Katherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903243/
https://ncbi.nlm.nih.gov/pubmed/24395804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322229111
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