UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

Uncoupling protein 2 (UCP2) is involved in various physiological and pathological processes such as insulin secretion, stem cell differentiation, cancer, and aging. However, its biochemical and physiological function is still under debate. Here we show that UCP2 is a metabolite transporter that regu...

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Autori principali: Vozza, Angelo, Parisi, Giovanni, De Leonardis, Francesco, Lasorsa, Francesco M., Castegna, Alessandra, Amorese, Daniela, Marmo, Raffaele, Calcagnile, Valeria M., Palmieri, Luigi, Ricquier, Daniel, Paradies, Eleonora, Scarcia, Pasquale, Palmieri, Ferdinando, Bouillaud, Frédéric, Fiermonte, Giuseppe
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903233/
https://ncbi.nlm.nih.gov/pubmed/24395786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317400111
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