UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

Uncoupling protein 2 (UCP2) is involved in various physiological and pathological processes such as insulin secretion, stem cell differentiation, cancer, and aging. However, its biochemical and physiological function is still under debate. Here we show that UCP2 is a metabolite transporter that regu...

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Detalhes bibliográficos
Main Authors: Vozza, Angelo, Parisi, Giovanni, De Leonardis, Francesco, Lasorsa, Francesco M., Castegna, Alessandra, Amorese, Daniela, Marmo, Raffaele, Calcagnile, Valeria M., Palmieri, Luigi, Ricquier, Daniel, Paradies, Eleonora, Scarcia, Pasquale, Palmieri, Ferdinando, Bouillaud, Frédéric, Fiermonte, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903233/
https://ncbi.nlm.nih.gov/pubmed/24395786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317400111
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