In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene

High-grade serous ovarian cancers are characterized by widespread recurrent copy number alterations. Although some regions of copy number change harbor known oncogenes and tumor suppressor genes, the genes targeted by the majority of amplified or deleted regions in ovarian cancer remain undefined. H...

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Bibliografische gegevens
Hoofdauteurs: Dunn, Gavin P., Cheung, Hiu Wing, Agarwalla, Pankaj K., Thomas, Sapana, Zektser, Yulia, Karst, Alison M., Boehm, Jesse S., Weir, Barbara A., Berlin, Aaron M., Zou, Lihua, Getz, Gad, Liu, Joyce F., Hirsch, Michelle, Vazquez, Francisca, Root, David E., Beroukhim, Rameen, Drapkin, Ronny, Hahn, William C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903232/
https://ncbi.nlm.nih.gov/pubmed/24385586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311909111
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