Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance

Errors are inherent in all biological systems. Errors in protein translation are particularly frequent giving rise to a collection of protein quasi-species, the diversity of which will vary according to the error rate. As mistranslation rates rise, these new proteins could produce new phenotypes, al...

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Detaylı Bibliyografya
Asıl Yazarlar: Javid, Babak, Sorrentino, Flavia, Toosky, Melody, Zheng, Wen, Pinkham, Jessica T., Jain, Nina, Pan, Miaomiao, Deighan, Padraig, Rubin, Eric J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903211/
https://ncbi.nlm.nih.gov/pubmed/24395793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317580111
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