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Straightforward detection of SNPs in double-stranded DNA by using exonuclease III/nuclease S1/PNA system
Single-nucleotide polymorphisms (SNPs) in double-stranded DNA (dsDNA) have been straightforwardly genotyped by matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry (MALDI-TOF MS). Peptide nucleic acid (PNA), a DNA analog, was used as a probe molecule. In its presence, genomi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390314/ https://ncbi.nlm.nih.gov/pubmed/14982961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh039 |
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