Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies
The Escherichia coli AlkB protein was recently found to repair cytotoxic DNA lesions 1-methyladenine and 3-methylcytosine by using a novel iron-catalyzed oxidative demethylation mechanism. Three human homologs, ABH1, ABH2 and ABH3, have been identified, and two of them, ABH2 and ABH3, were shown to...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15004242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh319 |
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