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The role of demethylase AlkB homologs in cancer

The AlkB family (ALKBH1-8 and FTO), a member of the Fe (II)- and α-ketoglutarate-dependent dioxygenase superfamily, has shown the ability to catalyze the demethylation of a variety of substrates, including DNA, RNA, and histones. Methylation is one of the natural organisms’ most prevalent forms of e...

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Autores principales: Qiao Li, Qingsan Zhu
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2023-03-01
Colección:Frontiers in Oncology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fonc.2023.1153463/full
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