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Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation
γH2AX formation by phosphorylation of the histone variant H2AX is the key process in the repair of DNA lesions including those arising at fragile sites under replication stress. Here we demonstrate that H2AX is dynamically reorganized to preoccupy γH2AX hotspots on increased replication stress by ac...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902941/ https://ncbi.nlm.nih.gov/pubmed/24163101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt951 |
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