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5′-Untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation

Upstream AUGs (uAUGs) and upstream open reading frames (uORFs) are common features of mRNAs that encode regulatory proteins and have been shown to profoundly influence translation of the main ORF. In this study, we employed a series of artificial 5′-untranslated regions (5′-UTRs) containing one or m...

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書目詳細資料
Main Authors: Wang, Xue-Qing, Rothnagel, Joseph A.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC390293/
https://ncbi.nlm.nih.gov/pubmed/14990743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh305
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