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5′-Untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation
Upstream AUGs (uAUGs) and upstream open reading frames (uORFs) are common features of mRNAs that encode regulatory proteins and have been shown to profoundly influence translation of the main ORF. In this study, we employed a series of artificial 5′-untranslated regions (5′-UTRs) containing one or m...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390293/ https://ncbi.nlm.nih.gov/pubmed/14990743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh305 |
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