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A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation

The C-terminal domain (CTD) of RNA polymerase II is sequentially modified for recruitment of numerous accessory factors during transcription. One such factor is Spt6, which couples transcription elongation with histone chaperone activity and the regulation of H3 lysine 36 methylation. Here, we show...

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Autori principali: Dronamraju, Raghuvar, Strahl, Brian D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902893/
https://ncbi.nlm.nih.gov/pubmed/24163256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1003
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