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DNA elements important for CAG·CTG repeat thresholds in Saccharomyces cerevisiae

Trinucleotide repeat (TNR) instability is of interest because of its central role in human diseases such as Huntington’s and its unique genetic features. One distinctive characteristic of TNR instability is a threshold, defined as a minimal repeat length that confers frequent mutations. While thresh...

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Hlavní autoři: Dixon, Michael J., Lahue, Robert S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC390281/
https://ncbi.nlm.nih.gov/pubmed/14982954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh292
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