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Enhancement of Polysialic Acid Expression Improves Function of Embryonic Stem-Derived Dopamine Neuron Grafts in Parkinsonian Mice

There has been considerable progress in obtaining engraftable embryonic stem (ES) cell-derived midbrain dopamine neurons for cell replacement therapy in models of Parkinson’s disease; however, limited integration and striatal reinnervation of ES-derived grafts remain a major challenge for future cli...

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Hlavní autoři: Battista, Daniela, Ganat, Yosif, El Maarouf, Abderrahman, Studer, Lorenz, Rutishauser, Urs
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902288/
https://ncbi.nlm.nih.gov/pubmed/24311700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0084
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