Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

Using a systems biology approach, we discovered and dissected a three-way interaction between the immune system, the intestinal epithelium and the microbiota. We found that, in the absence of B cells, or of IgA, and in the presence of the microbiota, the intestinal epithelium launches its own protec...

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Detalhes bibliográficos
Main Authors: Shulzhenko, Natalia, Morgun, Andrey, Hsiao, William, Battle, Michele, Yao, Michael, Gavrilova, Oksana, Orandle, Marlene, Mayer, Lloyd, Macpherson, Andrew J, McCoy, Kathy D, Fraser-Liggett, Claire, Matzinger, Polly
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902046/
https://ncbi.nlm.nih.gov/pubmed/22101768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2505
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