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Spontaneous mutation in the Cd79b gene leads to a block in B lymphocyte development at the C′ (early pre-B) stage
We discovered B lymphocyte deficient mice within a group of B10.A-CD45.1 mice, and established that this deficiency was a recessively inherited trait. Gene mapping and sequence analysis showed a mutation in the 3(rd) exon of the Cd79b gene (c.224G>A) that leads to the generation of a stop codon (...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787784/ https://ncbi.nlm.nih.gov/pubmed/19727123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.70 |
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