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MicroRNA dependent regulation of DNMT-1 and tumor suppressor gene expression by Interleukin-6 in human malignant cholangiocytes

Although the inflammation-associated cytokine Interleukin-6 (IL-6) has been implicated in cholangiocarcinoma growth, the relationship between IL-6 and oncogenic changes is unknown. IL-6 can increase expression of DNA methyltransferase 1 (DNMT-1) and epigenetically regulate the expression of several...

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Bibliografski detalji
Glavni autori: Braconi, Chiara, Huang, Nianyuan, Patel, Tushar
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902044/
https://ncbi.nlm.nih.gov/pubmed/20146264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23381
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