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Targeting the IL-6 Dependent Phenotype Can Identify Novel Therapies for Cholangiocarcinoma

BACKGROUND: The need for new therapies for cholangiocarcinoma is highlighted by their poor prognosis and refractoriness to chemotherapy. Increased production of Interleukin-6 promotes cholangiocarcinoma growth and contributes to chemoresistance by activating cell survival mechanisms. We sought to id...

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Autors principals: Braconi, Chiara, Swenson, Erica, Kogure, Takayuki, Huang, Nianyuan, Patel, Tushar
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002961/
https://ncbi.nlm.nih.gov/pubmed/21179572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015195
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