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Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells

Because DNA methyltransferase (DNMT) inhibitors like azacytidine and decitabine are known to be effective in the clinic for diseases like myelodysplastic syndromes that may result in part from transcriptional dysregulation due to epigenetic changes, there is interest in developing novel DNMT inhibit...

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Bibliografische gegevens
Hoofdauteurs: Billam, Madhavi, Sobolewski, Michele D., Davidson, Nancy E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901992/
https://ncbi.nlm.nih.gov/pubmed/19459041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0420-3
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