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The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines
Polyamine analogues have demonstrated significant activity against human breast cancer cell lines as single agents as well as in combination with other cytotoxic drugs. This study evaluates the ability of a polyamine analogue N(1), N(11)-bis(ethyl)norspermine (BENSpm) to synergize with six standard...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840063/ https://ncbi.nlm.nih.gov/pubmed/19727732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1112-8 |
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