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Hearing Impairment in Hypothyroid Dwarf Mice Caused by Mutations of the Thyroid Peroxidase Gene
Thyroid hormone (TH) is essential for proper cochlear development and function, and TH deficiencies cause variable hearing impairment in humans and mice. Thyroid peroxidase (TPO) catalyzes key reactions in TH synthesis, and TPO mutations have been found to underlie many cases of congenital hypothyro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901854/ https://ncbi.nlm.nih.gov/pubmed/24297261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-013-0427-7 |
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