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Image-Based Noninvasive Evaluation of Colorectal Mucosal Injury in Sheep Following Topical Application of Microbicides
BACKGROUND: Successful development of topical rectal microbicides requires preclinical evaluation in suitable large animal models. Our previous studies have demonstrated the benefits of high resolution optical coherence tomography (OCT) to visualize subclinical microbicide toxicity in the sheep vagi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901848/ https://ncbi.nlm.nih.gov/pubmed/24113407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/OLQ.0000000000000039 |
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