Anti-leukemia T cells in AML: TNF-α(+) CD8(+) T cells may escape detection and possibly reflect a stage of functional impairment

Leukemia-associated antigens such as proteinase-3 (PR3) and Wilms´ tumor protein-1 (WT-1) are potential targets of T-cell responses, which can be monitored by T-cell assays within vaccination trials and after allogeneic stem cell transplantation (SCT). In chronic myeloid leukemia (CML) an aberrant c...

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Detalhes bibliográficos
Main Authors: Flörcken, Anne, van Lessen, Antje, Terwey, Theis H., Dörken, Bernd, Arnold, Renate, Pezzutto, Antonio, Westermann, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901807/
https://ncbi.nlm.nih.gov/pubmed/23571180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.24250
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